AOSpine Knowledge Forum Deformity

Creating a common language and framework for researchers and clinicians

Goals

AOSpine KF Deformity aims to improve the care for patients with a spinal deformity by generating and disseminating meaningful and impactful clinical evidence.

They do this by engaging leading clinicians, researchers, and spine centers from around the world to perform evidence-based research and by disseminating the research findings and newfound knowledge through publications and presentations.

Ongoing research projects

  • AOSpine Comprehensive Classification of Adult Spinal Deformity (AOASD)

    Principal investigator:
    J Naresh-Babu 

    Co-Principal investigators:
    Manabu Ito, Jong-Beom Park, Kenny Kwan

    Goals:
    Aims to develop comprehensive classification that separates patients into clinically different subgroups that require different treatment strategies

  • * Spinal Deformity Intraoperative Monitoring (SDIM)

    Principal investigator:
    Stephen Lewis

    Co-Principal investigators:
    Lawrence Lenke, Nasir Quraishi

    Goals:
    Aims to determine the incidence of intraoperative neuromonitoring alerts in complex, high-risk, spinal deformity surgeries and identify the events that lead to such alerts

    Remark:
    This project received co-funding from the Scoliosis Research Society (SRS) through an SRS Research Grant


    Documents:
    Publication summary

  • Complication Classification System of Spinal Deformity Surgery (CCS-SDS)

    Principal investigator:
    Sigurd Berven

    Co-Principal investigators:
    Lawrence Lenke, Christopher Shaffrey

    Goals:
    Aims to develop and validate a reliable system for categorizing and classifying various complications during and following adult spinal deformity surgery

  • Evaluation of neurologic complications associated with surgical correction of adult spinal deformity (Scoli-RISK 1): five-year extension

    A prospective, observational, multi-center study

    Principal investigator:
    Lawrence Lenke

    Co-Principal investigators:
    Michael Fehlings

    Goals:
    Aims to establish the long-term risk of neurologic deficit related to the surgical correction of adult spinal deformity and to identify characteristics associated with an increased risk of neurologic complications related to surgery at five-year postoperative

  • FLEXIbility in Scoliosis (FLEXIS)
    Comparison of dynamic radiographs in determining fusion level in adolescent idiopathic scoliosis correction

    Principal investigator:
    Kenny Kwan 

    Co-Principal investigators:
    Kenneth Cheung, Ahmet Alanay

    Goals:
    Aims to identify the dynamic radiograph(s) that can most accurately predict the curve behavior after surgical correction in patients diagnosed with adolescent idiopathic scoliosis

    Documents:
    Publication summary
  • Prospective Evaluation of Elderly Deformity Surgery (PEEDS): five-year extension

    A prospective observational, multicenter study

    Principal investigator:
    Stephen Lewis

    Co-Principal investigators:
    Sigurd Berven

    Goals:
    Aims to show an improvement in SRS-22 total score between baseline and 24 months and five years after surgery in patients at age 60 or older treated with major spinal reconstruction (spinal fusion of at least five levels) for adult spinal deformity

    Documents:
    Publication summary

* Award-winning project

Completed research projects

  • * Evaluation of neurologic complications associated with surgical correction of adult spinal deformity (Scoli-RISK 1)

    A prospective, observational, multi-center study

    Principal investigator:
    Lawrence Lenke

    Co-Principal investigators:
    Michael Fehlings

    Goals:
    Aim was to establish the risk of neurologic deficit related to surgical correction of adult spinal deformity and to identify characteristics associated with increased risk of neurologic complications related to the surgery

    Remark:
    This project received co-funding from the Scoliosis Research Society (SRS) and Norton Healthcare

    Documents:
    Publication summary

  • Identification of a core outcome set for spinal deformity surgery (COSSCO)

    Core Outcome Set for SCOliosis (COSSCO)

    Principal investigator:
    Marinus de Kleuver

    Co-Principal investigators:
    David Polly

    Goals:
    Aim was to develop a core outcome set specific to spinal deformity that represents the minimum that should be measured and reported in all outcome registries of a specific condition

    Documents:
    Publication summary

  • An international consensus on the appropriate treatment for adults with spinal deformity (ASD Consensus)

    Principal investigator:
    Sigurd Berven

    Co-Principal investigators:
    Marinus de Kleuver

    Goals:
    Aim was to identify goals of care and management strategies that are appropriate for adult spinal deformity patients based upon worldwide expert opinion

    Documents:
    Publication summary

  • An international consensus on the surgical treatment standards for adolescent idiopathic scoliosis (AIS Consensus)

    Principal investigator:
    Marinus de Kleuver

    Co-Principal investigators:
    Manabu Ito

    Goals:
    Aim was to investigate what constitutes optimal operative care for adolescent idiopathic scoliosis patients between 12 and 20 years of age with curves ranging from 40 to 90 degrees Cobb angle

    Documents:
    Publication summary

* Award-winning project

KF Deformity steering committee

Stephen Lewis

Chairperson
Toronto Western Hospital 
Toronto, Canada

Marinus de Kleuver

Past Chairperson
Radboud University Medical Center Nijmegen, the Netherlands

Lawrence Lenke

Columbia University New York,
New York, USA

Sigurd Berven

University of California San Francisco 
San Francisco, USA

Ahmed Alanay

Acibadem University School of Medicine 
Istanbul, Turkey

Yong Qiu

Nanjing University
Nanjing, China

Kenneth Cheung

The University of Hong Kong 
Hong Kong, China

Manabu Ito

National Hospital Organization Hokkaido Medical Center 
Sapporo, Japan

David Polly

University of Minnesota 
Minneapolis, USA

Christopher Shaffrey

Duke University Medical Center
Durham, USA


KF Deformity Associate Members

Saumyajit Basu, India
André Luis Fernandes Andújar, Brazil
Munish Gupta, USA
Kenny Kwan, Hong Kong
Yukihiro Matsuyama, Japan
Venugopal (KV) Menon, India
J Naresh Babu, India 
Jean Ouellet, Canada
Ferran Pellisé, Spain
Emiliano Vialle, Brazil


Knowledge Forum Manager

Yabin Wu

Yabin Wu

Research Project Manager

Other Knowledge Forums

KF Tumor

AOSpine KF Tumor

KF SCI

AOSpine KF Spinal Cord Injury (SCI)

KF Trauma

AOSpine KF Trauma

KF Degeneration

AOSpine KF Degenerative

“There is a myriad of outcome studies and instruments out there; everybody uses different tools to measure their quality of care. We help bring more rationale to the options that are available.”

Marinus de Kleuver, Past Chairperson KF Deformity, Research Commission member

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