AO Spine Knowledge Forum Trauma

Systematically bringing the world on the same page

Goals

AOSpine KF Trauma addresses the growing health care issue of spinal trauma with a goal to:

  • improve the care of all patients with (suspected) spinal column injury;
  • advance knowledge about patterns of spinal injury and their consequences;
  • develop reliable classification systems based on the systematic study of all available knowledge;
  • develop simple, clinically useful, diagnostic and therapeutic algorithms.

Ongoing research projects

  • Erector Spinae Plane Block and Analgesia
    Does erector spinae plane block decrease the amount of analgesia needed after mini-invasive posterior transpedicular stabilization in patients with vertebral body fracture. Are there any peri or postoperative complications?

    Principal investigator:
    Martin Holas

    Co-Principal investigator:
    Jakub Hlásny

    Goals:
    Aims to evaluate if the use of an erector spinae plane block (ESP) leads to reduction of analgesic demands in the perioperative period in patients undergoing Mini-invasive spinal surgery after fracture of the vertebral body in thoracic or lumbar spine.
  • AO Spine-DGOU Osteoporotic Fracture Classification System
    Principal investigator:
    Klaus Schnake

    Goals:
    To develop an easy and reliable classification system to support therapeutic decision making in Osteoporotic Vertebral-Fractures
  • AO Spine Post-traumatic Deformity (PTDEF)
    AO Spine post-traumatic deformity and its relation to health-related quality of life outcomes in spine trauma (AOSpine PTDEF)

    Principal investigator:
    Lorin M. Benneker

    Co-Principal investigators:
    Gregory Schroeder
    Cumhur Öner

    Goals:
    1. Aims to establish a definition for post-traumatic deformity through systematic review of the literature.
    2. Aims to find consensus among experts on factors clinically significant to post-traumatic deformity.
    3. Aims to understand the relationship between post-traumatic deformity and the long-term health-related quality of life outcomes measured with the ODI in patients who have undergone a traumatic injury of their spine.

     

  • * Thoracolumbar Burst Fractures (AOSpine TLA3-A4) in Neurologically Intact Patients

    An observational, multicenter cohort study comparing surgical versus non-surgical treatment

    Principal investigator:
    Marcel Dvorak

    Co-Principal investigators:
    Cumhur Öner

    Goals:
    Aims to establish and quantify the difference in the patients’ clinical outcomes after surgical treatment as compared to non-surgical treatment of thoracolumbar burst fractures within the first year after treatment with the Oswestry Disability Index (ODI)

    Documents:
    Read more about the study in the AO Spine Newsletter 

    ClinicalTrials.gov Identifier: NCT02827214

  • AO Spine Patient and Clinician-reported Spine Trauma Outcome Measures (PROST, CROST)

    Development of an AO Spine trauma outcome instrument

    Principal investigator:
    Cumhur Öner

    Goals:
    Aims to develop and validate a multidisciplinary and universal outcome instrument for spinal trauma patients, which includes both the patients’ and health professionals’ perspective on health and functioning:
    Phase 1: Identify the most common problems in patients with spinal trauma from the clinical and patient perspective, using the International Classification of Functioning, Disability and Health (ICF) categories as reference
    Phase 2: Consensus meeting to agree on a core set of ICF categories that are relevant to measure patient reported functioning, disability and health outcomes
    Phase 3: Development and validation of disease specific outcome instruments for spine trauma—AOSpine PROST and AO Spine CROST
    Phase 4: Extend and validate AO Spine PROST to patients with complete traumatic spinal cord injury

  • ** AO Spine Injury Classification System

    Development of a spine trauma injury classification system

    Principal investigator:
    Alex Vaccaro

    Co-Principal investigators:
    Cumhur Öner

    Goals:
    Aims to develop and validate a comprehensive classification system of traumatic spine injuries
    Phase 1: thoracolumbar system, completion 
    Phase 2: subaxial system, disseminating
    Phase 3: sacral system, disseminating and executing
    Phase 4: upper cervical system, disseminating and executing

    Documents:
    Classification toolkits and videos 
    Publication summary

* This AO Spine-sponsored study is executed with support from AO Clinical Investigation and Documentation (AO CID).
** Award-winning project

Completed research projects

  • AO Spine Trauma Focus Issue 2017

    Principal investigator:
    Alex Vaccaro

    Co-Principal investigators:
    Greg Schroeder

    Goals:
    The Spine Trauma Focus Issue aimed to synthesize the latest available knowledge regarding spine trauma and spinal cord injury controversies, AO Spine outcome instruments, AO Spine Classification systems and presentation of cases.

    Documents:
    Spine Trauma Focus Issue

  • Effect of Riluzole on Osteogenic Differentiation

    Effect of riluzole on osteogenetic differentiation of human mesenchymal stem cells and human osteoblasts

    Principal investigator:
    Alex Vaccaro

    Co-Principal investigators:
    Cumhur Öner

    Goals:
    Aimed to understand the effects of Riluzole on mesenchymal stem cells' ability to convert to osteoblasts, on osteogenic differentiation, and possible toxicity of the drug on these cells

    Documents:
    Publication summary

  • Value of CT and MRI

    The additional value of computed tomography (CT) and magnetic resonance imaging (MRI) in determining the fracture severity and management in spinal column injuries

    Principal investigator:
    Shanmuganathan Rajasekaran

    Goals:
    Aimed to define and determine the value of a CT scan and an MRI in addition to plain radiographs in a cohort of spinal fractures of various severities

    Documents:
    Publication summary

KF Trauma steering committee

Cumhur Öner

Chairperson 
University Medical Center 
Utrecht, the Netherlands

Alex Vaccaro

Past Chairperson 
Thomas Jefferson University 
Philadelphia, USA

Jens Chapman

Swedish Neuroscience Institute 
Seattle, USA

Frank Kandziora

Unfallklinik Frankfurt
Frankfurt, Germany

Shanmuganathan Rajasekaram

Shanmuganathan Rajasekaran

Ganga Hospital 
Coimbatore, India

Marcel Dvorak

Vancouver General Hospital
Vancouver, Canada

Klaus Schnake

Schön Klinik Nürnberg Fürth
Fürth, Germany

Lorin Benneker

Inselspital, University of Bern
Bern, Switzerland

Emiliano Vialle

Cajuru Hospital, Catholic University of Paraná 
Curitiba, Brazil


KF Trauma Associate Members

Gaurav Dhakal, National Trauma Center, National Academy of Medical Sciences, Kathmandu, Nepal
Mohammad El-Sharkawi, Assiut University Medical School, Assiut, Egypt
Andrei Fernandes Joaquim, University of Campinas, Campinas, Brazil
Martin Holas, Teaching Hospital F. D. Roosevelt, Banská Bystrica, Slovakia
Rishi Kanna, Ganga Hospital, Coimbatore, India
Sander Muijs, University Medical Center Utrecht, Utrecht, the Netherlands
Eugen Cezar Popescu, “Prof. Dr. N. Oblu” Emergency Hospital, Bucharest, Romania
Greg Schroeder, Thomas Jefferson University, PA, USA, USA
Jin W. Tee, The Alfred Hospital, Melbourne, VA, Australia


Knowledge Forum Manager

Olesja Hazenbiller

Olesja Hazenbiller

Research Project Manager

Other Knowledge Forums

KF Tumor

AOSpine KF Tumor

KF Deformity

AOSpine KF Deformity

KF SCI

AOSpine KF Spinal Cord Injury (SCI)

KF Degeneration

AOSpine KF Degenerative

“Simple, clinically useful, diagnostic and therapeutic algorithms will help spread knowledge and understanding of spinal injuries, reduce preventable disability, and rationalize treatment.” 

Cumhur Öner, Chairperson KF Trauma, Research Commission member

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