AOSpine Research Network (AOSRN) 

Research Network

The AOSRN is an affiliation of research experts conducting collaborative applied/translational research for the treatment of spinal pathologies. The AOSRN represents AOSpine's experimental research strategic initiative.


Who is behind the AOSRN?

Under the leadership of a delegate appointed by the AOSpine Research Commission, the AOSRN includes members of various disciplines from around the world. They are predominantly AOSpine investigators who have previously received or are currently holding AOSRN research grants in the focus field. However, any AOSpine investigators conducting research in the focus field through AOSpine is able to join. 

Research Focus

From 2007 until 2016, the focus of the AOSRN is degeneration and regeneration of the intervertebral disc.

AOSRN Granted Projects

We are currently sponsoring four projects: 

Project Title​ Research Area​
End Date
Grant Type
Tugan Muftuler
Medical College of Wisconsin

Quantitative MRI of the intervertebral disc degeneration

Disc Degeneration:
MRI Diagnostics​
Jul 2016 SRN '12 — Single Center
Keita Ito
Eindhoven University of Technology

Björn Meij
Utrecht University

Notochordal cell technology for intervertebral disc regeneration​

Disc Regeneration:
Notochordal Cells
Aug 2016
SRN '11 —Consortium
Lisbet Haglund
McGill University​​

Biological repair of the degenerate intervertebral disc​

Disc Regeneration: Mechanobiology​​ Sept 2016
SRN '11 — Single Center
Barbara Chan
The University of Hong Kong

Biomaterial-assisted cell-based therapy for disc degeneration​

Disc Regeneration:
Biomaterials and Stem Cells​
Oct 2016
SRN '11 —Consortium

AO Foundation's Research Institute, Davos (ARI) 

The goal of ARI is to contribute high quality scientific research and future developments within musculoskeletal system disorders and trauma, including spine. For further information, please click here.

ARI is currently conducting a project within AOSpine:

Investigators​ Project Title​ Research Area​ End Date​
Mauro Alini
Sibylle Grad
Stem cell based intervertebral disc regeneration – evaluation of cell carrier and delivery strategy for
pre-clinical application
Mesenchymal Stem Cells and invivo component Dec 2016​