CID

AOSpine Knowledge Forum Deformity

The AOSpine KF Deformity is an international working group composed of 10 steering committee members who meet on a regular basis to discuss research, assess the best evidence for current practices, and formulate clinical studies in the domain of spinal deformities. It is charged with conducting clinical research, developing AOSpine classifications, guidelines, and outcome measures.

 

 

 

Steering Committee


Marinus de Kleuver
Chairperson
Radboud University Medical Center, Nijmegen, Netherlands

Lawrence Lenke
Past Chairperson 
Columbia University New York, NY, USA

Sigurd Berven University of California San Francisco
San Francisco, CA, USA

Ahmed Alanay,
Acibadem University School of Medicine
Istanbul, Turkey

Stephen Lewis
Toronto Western Hospital
Toronto, ON, Canada


Yong Qiu
Nanjing University
Nanjing, China


Kenneth Cheung 
The University of Hong Kong
Hong Kong, China

Manabu Ito
National Hospital Organization Hokkaido Medical Center
Sapporo, Japan

David Polly
University of Minnesota 
Minneapolis, MN, USA

Christopher Shaffrey 
University of Virginia 
Charlottesville, VA, USA
 

Project overview

Status: Planning
​Project Title ​Investigator(s) ​Aim Outcomes
​AOASD  Classification ​AOSpine Comprehensive Classification of Adult Spinal Deformity ​PI: Naresh-Babu J
Co-PI: Manabu Ito, Jong-Beom Park
​To develop a comprehensive classification that separates patients into clinically different sub-groups that require different treatment strategies.
​SDIM ​Spinal Deformity Intraoperative Monitoring (SDIM): Understanding and managing intraoperative neuromonitoring changes during spinal deformity surgery ​PI: Stephen Lewis
Co-PI: Lawrence Lenke
​To determine the incidence of intraoperative neuromonitoring alerts in complex, high-risk spinal deformity surgeries and identify the events that lead to such alerts. ​Publication summary
​CCS-SDS ​Complication Classification System of Spinal Deformity Surgery (CCS-SDS) ​PI: Sigurd Berven
Co-PI: Lawrence Lenke, Christopher Shaffrey

​To develop and validate a reliable system for categorizing and classifying various complications during and following adult spinal deformity surgery.

Status: Executing​ ​ ​ ​
​Project Title ​Investigator(s) ​Aim Outcomes
​Scoli-RISK-1:
5-year extension
​Evaluation of neurologic compli-cations associated with surgical correction of adult spinal defor¬mity (Scoli-RISK 1): a prospective, observational, multi-center study ​PI: Lawrence Lenke
Co-PI: Michael Fehlings
​To establish the long term risk of neurologic deficit related to surgical correction of adult spinal deformity and to identify characteristics associated with increased risk of neurologic complications related to the surgery at 5-year postoperative.
FLEXIS ​FLEXIbility in Scoliosis (FLEXIS): Comparison of dynamic radiographs in determining fusion level in adolescent idiopathic scoliosis correction
PI: Kenny Kwan
Co-PI: Kenneth Cheung, Ahmet Alanay

To identify the dynamic radiograph(s) that can most accurately predict the curve behavior after surgical correction in patients diagnosed with adolescent idiopathic scoliosis.



PEEDS &
PEEDS: 5-year extension
​Prospective Evaluation of Elderly Deformity Surgery (PEEDS): a prospective observational, multicenter study ​PI: Stephen Lewis
Co-PI: Sigurd Berven

​To show an improvement in SRS-22 total score between baseline and 24 months and 5 years after surgery in patients at age 60 or older treated with major spinal reconstruction (spinal fusion of at least 5 levels) for adult spinal deformity.

Publication summary
Status: Publishing ​ ​ ​ ​
​Project Title ​Investigator(s) ​Aim Outcomes
Scoli-RISK-1 Evaluation of neurologic compli-cations associated with surgical correction of adult spinal defor¬mity (Scoli-RISK 1): a prospective, observational, multi-center study
PI: Lawrence Lenke
Co-PI: Michael Fehlings

To establish the risk of neurologic deficit related to surgical correction of adult spinal deformity and to identify characteristics associated with increased risk of neurologic complications related to the surgery.
Remark: This project received co-funding from the Scoliosis Research Society (SRS) and Norton Healthcare. 

Publication summary​​

Status: Completed ​ ​ ​ ​
​Project Title ​Investigator(s) ​Aim Outcomes
​COSSCO

​Identification of a core outcome set for spinal deformity surgery (Core Outcome Set for SCOliosis—COSSCO)

​PI: Marinus de Kleuver
Co-PI: David Polly

​To develop a core outcome set specific to spinal deformity that represents the minimum that should be measured and reported in all outcome registries of a specific condition.

Publication summary
​ASD Consensus ​An international consensus on the appropriate treatment for adults with spinal deformity ​PI: Sigurd Berven
Co-PI: Marinus de Kleuver

​To identify goals of care and management strategies that are appropriate for adult spinal deformity patients based upon worldwide expert opinion.

Publication summary
AIS Consensus An international consensus on the surgical treatment standards for adolescent idiopathic scoliosis
PI: Marinus de Kleuver
Co-PI: Manabu Ito

To investigate what constitutes optimal operative care for adolescent idiopathic scoliosis patients between 12 and 20 years of age with curves ranging from 40 to 90 degrees Cobb angle.

Publication summary